Obstructive sleep apnoea & fatty liver disease | Dr Jonathan Hazlehurst

September 6, 2019 - Sleep Apnea

Dr Hazlehurst offers research study on the nature of the connection in between obstructive sleep apnoea (OSA) and also fatty liver condition.

Obstructive rest apnoea (or apnea) is characterised by upper respiratory tract blockage throughout rest leading to recurring hypoxia. Obstructive sleep apnoea is widely known to be related to a raised danger of cardio condition, yet is likewise gotten in touch with other illness consisting of non-alcoholic fatty liver condition.

Dr Hazlehurst’s work investigates the mechanisms through which the liver metabolises fat to find out even more about the link in between obstructive rest apnoea and fatty liver condition. His experiments suggest that obstructive rest apnoea is connected with activation of the hypothalamic pituitary adrenal (HPA) axis but antagonism of the glucocorticoid receptor is unlikely to avoid the connected metabolic illness.

Dr Jonathan Hazlehurst is an Academic Clinical Lecturer at the University of Birmingham.

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